Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tpxThiol peroxidase Tpx; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (197 aa)    
Predicted Functional Partners:
sodB
Fe/Mn superoxide dismutase SodB; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.829
selR
methionine-R-sulfoxide reductase SelR; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.716
fur
Transcriptional repressor of iron homeostasis Fur; Belongs to the Fur family.
   
  
 0.627
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
   
    0.589
SO_4141
Oxidoreductase short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
    0.587
yfiA
Ribosomal associated cold shock response protein YfiA.
   
    0.569
ahpF
Alkyl hydroperoxide reductase flavoprotein component AhpF.
   
  
 0.546
gor
Glutathione-disulfide reductase Gor.
  
  
 0.533
SO_3339
Outer membrane porin OmpA family.
  
  
 0.531
glnS
glutaminyl-tRNA synthetase GlnS.
  
    0.521
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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