| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| murF | yggS | SO_4223 | SO_3352 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.629 |
| pilT | pilU | SO_3351 | SO_3350 | Pilus retraction protein PilT. | Pilus retraction ATPase PilU. | 0.850 |
| pilT | proC | SO_3351 | SO_3354 | Pilus retraction protein PilT. | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.421 |
| pilT | yggS | SO_3351 | SO_3352 | Pilus retraction protein PilT. | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.627 |
| pilU | pilT | SO_3350 | SO_3351 | Pilus retraction ATPase PilU. | Pilus retraction protein PilT. | 0.850 |
| pilU | proC | SO_3350 | SO_3354 | Pilus retraction ATPase PilU. | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.420 |
| pilU | yggS | SO_3350 | SO_3352 | Pilus retraction ATPase PilU. | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.617 |
| proC | pilT | SO_3354 | SO_3351 | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Pilus retraction protein PilT. | 0.421 |
| proC | pilU | SO_3354 | SO_3350 | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Pilus retraction ATPase PilU. | 0.420 |
| proC | yggS | SO_3354 | SO_3352 | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.888 |
| proC | yggT | SO_3354 | SO_3355 | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Inner membrane osmoregulator protein YggT. | 0.744 |
| rlmN | yggS | SO_3315 | SO_3352 | 23S rRNA (adenine2503-C2)-methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.652 |
| rplX | rpmC | SO_0242 | SO_0239 | 50S ribosomal protein L24 RplX; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 50S ribosomal protein L29 RpmC; Belongs to the universal ribosomal protein uL29 family. | 0.999 |
| rplX | yggS | SO_0242 | SO_3352 | 50S ribosomal protein L24 RplX; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.588 |
| rpmC | rplX | SO_0239 | SO_0242 | 50S ribosomal protein L29 RpmC; Belongs to the universal ribosomal protein uL29 family. | 50S ribosomal protein L24 RplX; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.999 |
| rpmC | yggS | SO_0239 | SO_3352 | 50S ribosomal protein L29 RpmC; Belongs to the universal ribosomal protein uL29 family. | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.590 |
| yfiH | yggS | SO_3578 | SO_3352 | Uncharacterized protein YfiH; Belongs to the multicopper oxidase YfiH/RL5 family. | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.797 |
| yggS | murF | SO_3352 | SO_4223 | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.629 |
| yggS | pilT | SO_3352 | SO_3351 | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pilus retraction protein PilT. | 0.627 |
| yggS | pilU | SO_3352 | SO_3350 | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pilus retraction ATPase PilU. | 0.617 |