| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_3357 | proC | SO_3357 | SO_3354 | Outer membrane protein. | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.580 |
| SO_3357 | yggS | SO_3357 | SO_3352 | Outer membrane protein. | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.465 |
| SO_3357 | yggT | SO_3357 | SO_3355 | Outer membrane protein. | Inner membrane osmoregulator protein YggT. | 0.688 |
| SO_3357 | yggU | SO_3357 | SO_3356 | Outer membrane protein. | Protein of unknown function DUF167 YggU; Belongs to the UPF0235 family. | 0.671 |
| SO_3357 | yggV | SO_3357 | SO_3358 | Outer membrane protein. | Non-canonical purine NTP pyrophosphatase YggV; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.845 |
| SO_3357 | yggW | SO_3357 | SO_3359 | Outer membrane protein. | Radical SAM superfamily protein YggW; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.636 |
| ftsA | ftsZ | SO_4216 | SO_4215 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Cell division filament FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.999 |
| ftsA | yggS | SO_4216 | SO_3352 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.442 |
| ftsA | yggT | SO_4216 | SO_3355 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Inner membrane osmoregulator protein YggT. | 0.555 |
| ftsZ | ftsA | SO_4215 | SO_4216 | Cell division filament FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.999 |
| ftsZ | yggT | SO_4215 | SO_3355 | Cell division filament FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Inner membrane osmoregulator protein YggT. | 0.633 |
| mlaC | yggT | SO_3951 | SO_3355 | ABC-type phospholipid uptake (salvage) system periplasmic chaperone MlaC. | Inner membrane osmoregulator protein YggT. | 0.631 |
| proC | SO_3357 | SO_3354 | SO_3357 | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Outer membrane protein. | 0.580 |
| proC | yggS | SO_3354 | SO_3352 | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.906 |
| proC | yggT | SO_3354 | SO_3355 | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Inner membrane osmoregulator protein YggT. | 0.795 |
| proC | yggU | SO_3354 | SO_3356 | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Protein of unknown function DUF167 YggU; Belongs to the UPF0235 family. | 0.666 |
| proC | yggV | SO_3354 | SO_3358 | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Non-canonical purine NTP pyrophosphatase YggV; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.867 |
| proC | yggW | SO_3354 | SO_3359 | Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Radical SAM superfamily protein YggW; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.551 |
| yfjF | yggT | SO_1475 | SO_3355 | UPF0125 family protein YfjF; Belongs to the UPF0125 (RnfH) family. | Inner membrane osmoregulator protein YggT. | 0.602 |
| yggS | SO_3357 | SO_3352 | SO_3357 | PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Outer membrane protein. | 0.465 |