| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_1305 | rumA | SO_1305 | SO_3456 | Membrane protein. | 23S rRNA (uracil1939-C5)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.608 |
| SO_3458 | barA | SO_3458 | SO_3457 | Protein of unknown function DUF416. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.884 |
| SO_3458 | rumA | SO_3458 | SO_3456 | Protein of unknown function DUF416. | 23S rRNA (uracil1939-C5)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.544 |
| barA | SO_3458 | SO_3457 | SO_3458 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | Protein of unknown function DUF416. | 0.884 |
| barA | relA | SO_3457 | SO_3455 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.648 |
| barA | rsmB | SO_3457 | SO_0030 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 16S rRNA (cytosine967-C5)-methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.834 |
| barA | rsmB-2 | SO_3457 | SO_1575 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.819 |
| barA | rsmF | SO_3457 | SO_2609 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 16S rRNA (cytosine1407-C5)-methyltransferase RsmF; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.468 |
| barA | rumA | SO_3457 | SO_3456 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 23S rRNA (uracil1939-C5)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.649 |
| relA | barA | SO_3455 | SO_3457 | GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.648 |
| relA | rsmB | SO_3455 | SO_0030 | GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 16S rRNA (cytosine967-C5)-methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.541 |
| relA | rumA | SO_3455 | SO_3456 | GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 23S rRNA (uracil1939-C5)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.767 |
| rsmB | barA | SO_0030 | SO_3457 | 16S rRNA (cytosine967-C5)-methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.834 |
| rsmB | relA | SO_0030 | SO_3455 | 16S rRNA (cytosine967-C5)-methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.541 |
| rsmB | rsmF | SO_0030 | SO_2609 | 16S rRNA (cytosine967-C5)-methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 16S rRNA (cytosine1407-C5)-methyltransferase RsmF; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.520 |
| rsmB | rumA | SO_0030 | SO_3456 | 16S rRNA (cytosine967-C5)-methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 23S rRNA (uracil1939-C5)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.610 |
| rsmB-2 | barA | SO_1575 | SO_3457 | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.819 |
| rsmB-2 | rsmF | SO_1575 | SO_2609 | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 16S rRNA (cytosine1407-C5)-methyltransferase RsmF; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.409 |
| rsmB-2 | rumA | SO_1575 | SO_3456 | tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 23S rRNA (uracil1939-C5)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.548 |
| rsmF | barA | SO_2609 | SO_3457 | 16S rRNA (cytosine1407-C5)-methyltransferase RsmF; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.468 |