Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mexEHAE1 family efflux pump MFP component MexE; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (412 aa)    
Predicted Functional Partners:
mexF
HAE1 family efflux pump permease component MexF.
 
 
 0.998
vmeB
Proton-coupled multidrug efflux pump permease component VmeB.
 
 
 0.855
macB
ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.842
SO_4014
HAE1 family effllux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.789
macC
ABC-type macrolide export system secretin component MacC.
 
 
 0.782
vexA
RND-type multidrug/detergent efflux system permease component VexA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.752
SO_1882
HAE1 family efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.700
SO_3484
HAE1 family efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.695
tolC
Global secretion system secretin TolC.
  
 
 0.654
dinG
ATP-dependent helicase DinG; DNA-dependent ATPase and 5'-3' DNA helicase.
   
    0.602
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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