Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cysMCysteine synthase B CysM; Belongs to the cysteine synthase/cystathionine beta- synthase family. (292 aa)    
Predicted Functional Partners:
cysE
Serine acetyltransferase CysE.
 
 0.997
cysS
cysteinyl-tRNA synthetase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.929
wbnJ
O-antigen biosynthesis acetyltransferase WbnJ.
 
 
 0.916
metB
Cystathionine gamma-synthase MetB.
 
 
 0.896
cysJ
Sulfite reductase (NADPH) flavoprotein subunit CysJ; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
  
 
 0.873
cysD
Sulfate adenylyltransferase small subunit CysD.
  
  
 0.858
cysI
Sulfite reductase (NADPH) siroheme FeS subunit CysI; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.851
metY
O-acetylhomoserine (thiol)-lyase MetY.
  
  
 0.827
mdeA
Methionine gamma-lyase MdeA.
 
 
 0.825
metC
Cystathionine beta-lyase MetC.
  
 
 0.814
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (32%) [HD]