Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hmuXHeme iron utilization protein HmuX. (186 aa)    
Predicted Functional Partners:
hmuZ
FMN binding heme iron utilization protein HmuZ.
 
  
 0.993
hmuA
TonB-dependent heme/hemoglobin receptor HmuA.
 
  
 0.962
exbD-2
TonB1 energy transduction system for heme uptake inner membrane component ExbD.
  
  
 0.857
hemG
Oxygen-independent protoporphyrinogen oxidase HemG.
 
   
 0.801
hemG-3
Oxygen-independent protoporphyrinogen oxidase HemG.
 
   
 0.797
hemG-2
Oxygen-independent protoporphyrinogen oxidase HemG.
 
   
 0.777
hmuB
ABC-type hemin uptake system substrate-binding component HmuB.
 
  
 0.777
hmuC
ABC-type hemin uptake system permease component HmuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.763
exbB-2
TonB1 energy transduction system for heme uptake inner membrane component ExbB.
 
  
 0.756
hmuD
ABC-type hemin uptake system ATPase component HmuD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
 
  
 0.714
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.