Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
exbB-2TonB1 energy transduction system for heme uptake inner membrane component ExbB. (260 aa)    
Predicted Functional Partners:
exbD-2
TonB1 energy transduction system for heme uptake inner membrane component ExbD.
  
 
 0.999
exbD
TonB2 energy transduction system membrane anchored component ExbD.
 
 
 0.997
tonB
TonB1 energy transduction system for heme uptake energy transducer component TonB.
 
 
 0.978
hmuB
ABC-type hemin uptake system substrate-binding component HmuB.
 
  
 0.924
tonB-3
TonB mediated energy transduction system energy transducer component TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.922
tonB2
TonB2 mediated energy transduction system energy transducer component TonB2; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.920
tolR
TolA energy-transducing system inner membrane component TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.917
tonB-2
TonB mediated energy transduction system energy transducer component TonB.
  
 
 0.910
hmuA
TonB-dependent heme/hemoglobin receptor HmuA.
 
  
 0.828
hmuD
ABC-type hemin uptake system ATPase component HmuD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
  
  
 0.766
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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