| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| btuC | btuF | SO_1034 | SO_3709 | ABC-type cobalamin uptake system permease component BtuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | ABC-type cobalamin uptake system substrate-binding component BtuF. | 0.986 |
| btuC | hmuB | SO_1034 | SO_3673 | ABC-type cobalamin uptake system permease component BtuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | ABC-type hemin uptake system substrate-binding component HmuB. | 0.975 |
| btuC | hmuD | SO_1034 | SO_3675 | ABC-type cobalamin uptake system permease component BtuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | ABC-type hemin uptake system ATPase component HmuD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. | 0.985 |
| btuF | btuC | SO_3709 | SO_1034 | ABC-type cobalamin uptake system substrate-binding component BtuF. | ABC-type cobalamin uptake system permease component BtuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.986 |
| btuF | exbB-2 | SO_3709 | SO_3671 | ABC-type cobalamin uptake system substrate-binding component BtuF. | TonB1 energy transduction system for heme uptake inner membrane component ExbB. | 0.531 |
| btuF | hmuB | SO_3709 | SO_3673 | ABC-type cobalamin uptake system substrate-binding component BtuF. | ABC-type hemin uptake system substrate-binding component HmuB. | 0.757 |
| btuF | hmuC | SO_3709 | SO_3674 | ABC-type cobalamin uptake system substrate-binding component BtuF. | ABC-type hemin uptake system permease component HmuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.986 |
| btuF | hmuD | SO_3709 | SO_3675 | ABC-type cobalamin uptake system substrate-binding component BtuF. | ABC-type hemin uptake system ATPase component HmuD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. | 0.980 |
| btuF | hmuZ | SO_3709 | SO_3667 | ABC-type cobalamin uptake system substrate-binding component BtuF. | FMN binding heme iron utilization protein HmuZ. | 0.716 |
| cobQ | hmuD | SO_1038 | SO_3675 | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | ABC-type hemin uptake system ATPase component HmuD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. | 0.798 |
| exbB-2 | btuF | SO_3671 | SO_3709 | TonB1 energy transduction system for heme uptake inner membrane component ExbB. | ABC-type cobalamin uptake system substrate-binding component BtuF. | 0.531 |
| exbB-2 | hmuB | SO_3671 | SO_3673 | TonB1 energy transduction system for heme uptake inner membrane component ExbB. | ABC-type hemin uptake system substrate-binding component HmuB. | 0.919 |
| exbB-2 | hmuC | SO_3671 | SO_3674 | TonB1 energy transduction system for heme uptake inner membrane component ExbB. | ABC-type hemin uptake system permease component HmuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.753 |
| exbB-2 | hmuD | SO_3671 | SO_3675 | TonB1 energy transduction system for heme uptake inner membrane component ExbB. | ABC-type hemin uptake system ATPase component HmuD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. | 0.815 |
| exbB-2 | hmuZ | SO_3671 | SO_3667 | TonB1 energy transduction system for heme uptake inner membrane component ExbB. | FMN binding heme iron utilization protein HmuZ. | 0.608 |
| exbB-2 | irgA | SO_3671 | SO_4523 | TonB1 energy transduction system for heme uptake inner membrane component ExbB. | Iron-responsive TonB-dependent enterobactin receptor IrgA. | 0.483 |
| hmuB | btuC | SO_3673 | SO_1034 | ABC-type hemin uptake system substrate-binding component HmuB. | ABC-type cobalamin uptake system permease component BtuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.975 |
| hmuB | btuF | SO_3673 | SO_3709 | ABC-type hemin uptake system substrate-binding component HmuB. | ABC-type cobalamin uptake system substrate-binding component BtuF. | 0.757 |
| hmuB | exbB-2 | SO_3673 | SO_3671 | ABC-type hemin uptake system substrate-binding component HmuB. | TonB1 energy transduction system for heme uptake inner membrane component ExbB. | 0.919 |
| hmuB | hmuC | SO_3673 | SO_3674 | ABC-type hemin uptake system substrate-binding component HmuB. | ABC-type hemin uptake system permease component HmuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.999 |