Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SO_3690ABC-type macrolide family export system permease component 1. (399 aa)    
Predicted Functional Partners:
SO_3692
ABC-type macrolide family export system ATPase component.
 
 0.997
SO_3691
ABC-type macrolide family export system permease component 2.
 
  
  0.995
SO_3694
ABC-type macrolide family export system MFP component.
 
 
 0.991
macA
ABC-type macrolide export systemMFP component MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.816
lolD
ABC-type lipoprotein release system ATPase component LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
 
 
 0.732
SO_3688
Two component signal transduction system histidine kinase.
 
     0.723
macB
ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
0.680
attE
ABC-type export system ATPase component AttE.
 
 
 0.658
SO_1925
RND superfamily efflux pump MFP component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.608
SO_1705
ABC-type drugE1 family efflux system MFP component.
 
  
 0.606
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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