| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0587 | lptA | SO_0587 | SO_3959 | Glycerophosphodiester phosphodiesterase. | ABC-type lipopolysaccharide export system chaperone component LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | 0.790 |
| SO_0587 | nfnB | SO_0587 | SO_3715 | Glycerophosphodiester phosphodiesterase. | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | 0.789 |
| SO_0587 | wzx | SO_0587 | SO_3181 | Glycerophosphodiester phosphodiesterase. | O-antigen flippase Wzx. | 0.848 |
| birA | nfnB | SO_0214 | SO_3715 | Bifunctional biotin operon repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | 0.711 |
| gltD | nfnB | SO_1324 | SO_3715 | NADPH-dependent glutamate synthase small subunit GltD. | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | 0.811 |
| lptA | SO_0587 | SO_3959 | SO_0587 | ABC-type lipopolysaccharide export system chaperone component LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | Glycerophosphodiester phosphodiesterase. | 0.790 |
| lptA | nfnB | SO_3959 | SO_3715 | ABC-type lipopolysaccharide export system chaperone component LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | 0.718 |
| lptA | wzx | SO_3959 | SO_3181 | ABC-type lipopolysaccharide export system chaperone component LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | O-antigen flippase Wzx. | 0.737 |
| nfnB | SO_0587 | SO_3715 | SO_0587 | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | Glycerophosphodiester phosphodiesterase. | 0.789 |
| nfnB | birA | SO_3715 | SO_0214 | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | Bifunctional biotin operon repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.711 |
| nfnB | gltD | SO_3715 | SO_1324 | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | NADPH-dependent glutamate synthase small subunit GltD. | 0.811 |
| nfnB | lptA | SO_3715 | SO_3959 | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | ABC-type lipopolysaccharide export system chaperone component LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | 0.718 |
| nfnB | sye1 | SO_3715 | SO_2454 | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | NADH:flavin oxidoreductase Sye1. | 0.664 |
| nfnB | sye2 | SO_3715 | SO_2453 | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | NAD(P)H:flavin oxidoreductase Sye2. | 0.667 |
| nfnB | sye3 | SO_3715 | SO_4153 | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | NAD(P)H:flavin oxidoreductase Sye3. | 0.664 |
| nfnB | sye4 | SO_3715 | SO_3392 | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | NAD(P)H:flavin oxidoreductase Sye4. | 0.664 |
| nfnB | wzx | SO_3715 | SO_3181 | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | O-antigen flippase Wzx. | 0.795 |
| nfnB | ycaO | SO_3715 | SO_0795 | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | Protein involved in RimO-mediated beta-methylthiolation of ribosomal protein S12 YcaO. | 0.721 |
| sye1 | nfnB | SO_2454 | SO_3715 | NADH:flavin oxidoreductase Sye1. | Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB. | 0.664 |
| sye1 | sye2 | SO_2454 | SO_2453 | NADH:flavin oxidoreductase Sye1. | NAD(P)H:flavin oxidoreductase Sye2. | 0.930 |