Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SO_3762Membrane protein of unknown function DUF350. (299 aa)    
Predicted Functional Partners:
speE
Spermidine synthase SpeE; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
    0.943
SO_3765
PspA/IM30 family protein.
 
     0.884
SO_0733
Cold-shock DNA-binding domain protein.
   
    0.785
SO_3761
Predicted lipoprotein.
  
    0.766
pfaC
Multi-domain beta-ketoacyl synthase PfaC; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
     0.669
SO_2584
Membrane zinc metalloprotease.
  
     0.656
tonB-2
TonB mediated energy transduction system energy transducer component TonB.
  
    0.633
SO_2872
Membrane protein of unknown function DUF2069.
  
     0.595
glnE
[glutamate-ammonia-ligase] adenylyltransferase GlnE; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal [...]
       0.580
SO_1376
Integral membrane protein of unknown function DUF1449.
  
    0.573
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.