STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ygiFAdenylate cyclase YgiF. (503 aa)    
Predicted Functional Partners:
SO_2914
Protein of unknown function DUF412.
  
    0.634
sixA
Phosphohistidine phosphatase SixA; Belongs to the phosphoglycerate mutase family.
 
     0.630
SO_3770
Phosphate transport accessory protein of unknown function DUF47.
       0.589
ndpA
Nucleoid-associated protein NdpA.
  
     0.516
SO_3771
Inorganic phosphate transporter PiT family.
  
    0.481
SO_3772
SH3 domain protein.
       0.472
uspE
Universal stress protein UspE.
  
     0.464
glnE
[glutamate-ammonia-ligase] adenylyltransferase GlnE; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal [...]
 
    0.463
SO_4089
ABC-type efflux system MFP component.
   
    0.442
SO_2872
Membrane protein of unknown function DUF2069.
  
     0.427
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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