STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
putA-2Bifunctional proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1059 aa)    
Predicted Functional Partners:
prlS
Proline-responsive two component signal transduction system hybrid histidine kinase/resposne regulator PrlS.
  
  
 0.982
proC
Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.951
gdh
Glutamate dehydrogenase (NAD+) Gdh.
  
 
 0.945
gltB
NADPH-dependent glutamate synthase large subunit GltB.
  
 
 0.943
proB
Glutamate 5-kinase ProB; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
    
 0.940
proA
Gamma-glutamyl phosphate reductase ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.938
puuA
Gamma-glutamyl-putrescine synthase PuuA; Belongs to the glutamine synthetase family.
   
 
 0.934
glnA
Glutamine synthetase GlnA.
   
 
 0.934
gltD
NADPH-dependent glutamate synthase small subunit GltD.
     
 0.918
glsA
Glutaminase A GlsA; Belongs to the glutaminase family.
     
 0.909
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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