Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SO_3821Diguanylate phosphodiesterase. (515 aa)    
Predicted Functional Partners:
SO_0928
Diguanylate cyclase.
 
    0.978
SO_1055
Diguanylate cyclase with PAS and GAF sensory domains.
 
  
 0.978
SO_1646
Diguanylate cyclase.
 
   
 0.964
SO_3759
Diguanylate cyclase with GAF sensory domain.
 
   
 0.956
SO_0796
Diguanylate cyclase.
 
    0.950
SO_2049
Diguanylate cyclase.
 
    0.927
SO_3489
Diguanylate cyclase.
 
     0.925
SO_0569
Diguanylate cyclase with PAS sensory domain.
 
   
 0.915
SO_2174
Diguanylate cyclase with PAS sensory domain.
 
     0.913
SO_4407
Diguanylate cyclase.
 
     0.876
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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