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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
modETranscriptional repressor of molybdate and molybdenium cofactor metabolism ModE. (259 aa)    
Predicted Functional Partners:
modC
ABC-type molybdate uptake system ATPase component ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
 
 
 
 0.893
modA
ABC-type molybdate uptake system substrate-binding component ModA.
 
  
 0.830
modB
ABC-type molybdate uptake system permease component ModB; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
  
 0.822
mopI
Molybdenum-pterin binding protein MopI.
 
 
   0.740
moaE
Molybdenum cofactor biosynthesis protein E MoaE.
     
 0.701
birA
Bifunctional biotin operon repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
   
  
 0.682
SO_3967
Orphan ABC-type transport system substrate-binding component.
 
  
 0.636
modA-2
ABC-type molybdate uptake system substrate-binding component ModA.
 
  
 0.634
mogA
Molybdenum cofactor biosynthesis protein MogA.
 
 
 
 0.623
fdhE
Nitrate-inducible formate dehydrogenase chaperone FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
   
 0.602
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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