| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_3317 | SO_3442 | SO_3317 | SO_3442 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Nucleoside triphosphate pyrophosphohydrolase. | 0.902 |
| SO_3317 | adk | SO_3317 | SO_2018 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.900 |
| SO_3317 | cpdA | SO_3317 | SO_3901 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Cyclic 3', 5'-adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.908 |
| SO_3317 | ushA | SO_3317 | SO_2001 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA; Belongs to the 5'-nucleotidase family. | 0.979 |
| SO_3317 | yrfG | SO_3317 | SO_0177 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | HAD-superfamily hydrolase subfamily IA variant 3 protein family YrfG. | 0.901 |
| SO_3442 | SO_3317 | SO_3442 | SO_3317 | Nucleoside triphosphate pyrophosphohydrolase. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.902 |
| SO_3442 | adk | SO_3442 | SO_2018 | Nucleoside triphosphate pyrophosphohydrolase. | Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.912 |
| SO_3442 | cpdA | SO_3442 | SO_3901 | Nucleoside triphosphate pyrophosphohydrolase. | Cyclic 3', 5'-adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.924 |
| SO_3442 | cyaA | SO_3442 | SO_4312 | Nucleoside triphosphate pyrophosphohydrolase. | Adenylate cyclase CyaA; Belongs to the adenylyl cyclase class-1 family. | 0.901 |
| SO_3442 | cyaB | SO_3442 | SO_3778 | Nucleoside triphosphate pyrophosphohydrolase. | Cytoplasmic adenylate cyclase CyaB. | 0.900 |
| SO_3442 | cyaC | SO_3442 | SO_1329 | Nucleoside triphosphate pyrophosphohydrolase. | Adenylate cyclase CyaC. | 0.902 |
| SO_3442 | ushA | SO_3442 | SO_2001 | Nucleoside triphosphate pyrophosphohydrolase. | Bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA; Belongs to the 5'-nucleotidase family. | 0.902 |
| SO_3442 | yrfG | SO_3442 | SO_0177 | Nucleoside triphosphate pyrophosphohydrolase. | HAD-superfamily hydrolase subfamily IA variant 3 protein family YrfG. | 0.900 |
| SO_3900 | cpdA | SO_3900 | SO_3901 | Enzyme of unknown function UPF0227. | Cyclic 3', 5'-adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.939 |
| SO_3900 | nudF | SO_3900 | SO_3903 | Enzyme of unknown function UPF0227. | ADP-ribose pyrophosphatase NudF. | 0.717 |
| adk | SO_3317 | SO_2018 | SO_3317 | Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.900 |
| adk | SO_3442 | SO_2018 | SO_3442 | Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Nucleoside triphosphate pyrophosphohydrolase. | 0.912 |
| adk | cpdA | SO_2018 | SO_3901 | Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Cyclic 3', 5'-adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.905 |
| adk | ushA | SO_2018 | SO_2001 | Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA; Belongs to the 5'-nucleotidase family. | 0.900 |
| adk | yrfG | SO_2018 | SO_0177 | Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | HAD-superfamily hydrolase subfamily IA variant 3 protein family YrfG. | 0.903 |