Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hydBPeriplasmic [Fe-Fe] hydrogenase small subunit HydB. (106 aa)    
Predicted Functional Partners:
hydA
Periplasmic [Fe-Fe] hydrogenase large subunit HydA.
 
 
 0.991
hydG
Fe hydrogenase maturation rSAM protein HydG.
 
   
 0.963
hydE
Fe hydrogenase maturation rSAM protein HydE.
 
   
 0.902
hydF
Fe hydrogenase maturation GTPase HydF.
 
    0.884
hypF
NiFe hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
   
  
 0.833
apbC
Scaffold protein for [4Fe-4S] cluster assembly ApbC; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
 0.811
hypA
NiFe hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
      
 0.803
hypB
Ni2+-binding GTPase involved in regulation of NiFe hydrogenase expression and maturation HypB.
      
 0.802
fdh
Formate dehydrogenase cytochrome b Fdh.
 
     0.801
hypD
NiFe hydrogenase expression/formation protein HypD; Belongs to the HypD family.
      
 0.793
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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