STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fdhFormate dehydrogenase cytochrome b Fdh. (227 aa)    
Predicted Functional Partners:
purU
Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
  0.900
frmB
S-formylglutathione hydrolase FrmB; Serine hydrolase involved in the detoxification of formaldehyde.
     
  0.900
fdnH
Nitrate-inducible formate dehydrogenase iron-sulfur subunit FdnH; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
 
 
 0.875
fdhE
Nitrate-inducible formate dehydrogenase chaperone FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
  
 0.831
pckA
Phosphoenolpyruvate carboxykinase PckA; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
   
 
  0.808
fdnG
Nitrate-inducible formate dehydrogenase molybdopterin-binding subunit FdnG; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.805
hydA
Periplasmic [Fe-Fe] hydrogenase large subunit HydA.
 
     0.804
hydB
Periplasmic [Fe-Fe] hydrogenase small subunit HydB.
 
     0.804
mdh
NAD dependent malate dehydrogenase Mdh; Catalyzes the reversible oxidation of malate to oxaloacetate.
   
 
  0.801
fumB
Anaerobic fumarate hydratase FumB; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
   
 
  0.801
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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