STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrfAAmmonia-forming nitrite reductase NrfA; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine. Has even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH (By similarity); Belongs to the cytochrome c-552 family. (467 aa)    
Predicted Functional Partners:
napA
Periplasmic nitrate reductase molybdopterin-binding subunit NapA; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
  
 
 0.992
napB
Periplasmic nitrate reductase cytochrome c subunit NapB; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type CymA protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Not essential for nitrate reduction but confers advantage to the organism when grown on nitrate and thereby a fitness gain in utilizing nitrate. Belongs to the NapB family.
  
 
 0.978
cymA
Membrane anchored tetraheme cytochrome c CymA.
  
 
 0.976
hcp
Hydroxylamine reductase Hcp; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
    
 0.957
nrfD
Nitrite reductase quinol dehydrogenase component NrfD.
 
  
 0.928
glnA
Glutamine synthetase GlnA.
   
 
 0.908
puuA
Gamma-glutamyl-putrescine synthase PuuA; Belongs to the glutamine synthetase family.
     
 0.905
SO_0471
FMN-dependent nitronate monooxygenase.
     
  0.900
gdh
Glutamate dehydrogenase (NAD+) Gdh.
     
  0.900
sirD
Menaquinol oxidase SirD.
 
  
 0.895
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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