| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_4079 | obgE | SO_4079 | SO_3649 | Protein of unknown function DUF615; Belongs to the UPF0307 family. | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.716 |
| SO_4079 | rluD | SO_4079 | SO_3579 | Protein of unknown function DUF615; Belongs to the UPF0307 family. | 23S rRNA pseudouridine1911/1915/1917 synthase RluD; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.843 |
| SO_4079 | rplK | SO_4079 | SO_0220 | Protein of unknown function DUF615; Belongs to the UPF0307 family. | 50S ribosomal protein L11 RplK; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.694 |
| SO_4079 | rplM | SO_4079 | SO_3940 | Protein of unknown function DUF615; Belongs to the UPF0307 family. | 50S ribosomal protein L13 RplM; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.701 |
| SO_4079 | rplU | SO_4079 | SO_3652 | Protein of unknown function DUF615; Belongs to the UPF0307 family. | 50S ribosomal protein L21 RplU; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.705 |
| SO_4079 | rplX | SO_4079 | SO_0242 | Protein of unknown function DUF615; Belongs to the UPF0307 family. | 50S ribosomal protein L24 RplX; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.734 |
| SO_4079 | rpmF | SO_4079 | SO_2780 | Protein of unknown function DUF615; Belongs to the UPF0307 family. | 50S ribosomal protein L32 RpmF; Belongs to the bacterial ribosomal protein bL32 family. | 0.744 |
| SO_4079 | rpmG | SO_4079 | SO_4246 | Protein of unknown function DUF615; Belongs to the UPF0307 family. | 50S ribosomal protein L33 RpmG; Belongs to the bacterial ribosomal protein bL33 family. | 0.838 |
| SO_4079 | rpmH | SO_4079 | SO_0007 | Protein of unknown function DUF615; Belongs to the UPF0307 family. | 50S ribosomal protein L34 RpmH; Belongs to the bacterial ribosomal protein bL34 family. | 0.694 |
| SO_4079 | rsfS | SO_4079 | SO_1170 | Protein of unknown function DUF615; Belongs to the UPF0307 family. | Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.700 |
| obgE | SO_4079 | SO_3649 | SO_4079 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Protein of unknown function DUF615; Belongs to the UPF0307 family. | 0.716 |
| obgE | rluD | SO_3649 | SO_3579 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 23S rRNA pseudouridine1911/1915/1917 synthase RluD; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.922 |
| obgE | rplK | SO_3649 | SO_0220 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L11 RplK; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.893 |
| obgE | rplM | SO_3649 | SO_3940 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L13 RplM; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.883 |
| obgE | rplU | SO_3649 | SO_3652 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L21 RplU; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.978 |
| obgE | rplX | SO_3649 | SO_0242 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L24 RplX; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.876 |
| obgE | rpmF | SO_3649 | SO_2780 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L32 RpmF; Belongs to the bacterial ribosomal protein bL32 family. | 0.888 |
| obgE | rpmG | SO_3649 | SO_4246 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L33 RpmG; Belongs to the bacterial ribosomal protein bL33 family. | 0.865 |
| obgE | rpmH | SO_3649 | SO_0007 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L34 RpmH; Belongs to the bacterial ribosomal protein bL34 family. | 0.865 |
| obgE | rsfS | SO_3649 | SO_1170 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.904 |
