| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0490 | SO_4623 | SO_0490 | SO_4623 | Transmembrane transcriptional regulator CadC family. | Two component signal transduction system response regulator. | 0.571 |
| SO_0490 | SO_4718 | SO_0490 | SO_4718 | Transmembrane transcriptional regulator CadC family. | Tungstate-responsive two component Sigma54-dependent signal transduction system response regulator Fis family. | 0.613 |
| SO_0490 | ccmB | SO_0490 | SO_0262 | Transmembrane transcriptional regulator CadC family. | ABC-type heme export system permease component 1 CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | 0.652 |
| SO_0490 | ttrR | SO_0490 | SO_4157 | Transmembrane transcriptional regulator CadC family. | Two-component system, LuxR family, response regulator TtrR; Thiosulfate/tetrathionate-responsive two component signal transduction system response regulator TtrR. | 0.720 |
| SO_0490 | ttrS | SO_0490 | SO_4155 | Transmembrane transcriptional regulator CadC family. | Thiosulfate/tetrathionate-responsive two component signal transduction system histidine kinase TtrS. | 0.720 |
| SO_0859 | SO_1416 | SO_0859 | SO_1416 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator LuxR family. | 0.688 |
| SO_0859 | SO_4002 | SO_0859 | SO_4002 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.991 |
| SO_0859 | SO_4623 | SO_0859 | SO_4623 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator. | 0.927 |
| SO_0859 | SO_4718 | SO_0859 | SO_4718 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Tungstate-responsive two component Sigma54-dependent signal transduction system response regulator Fis family. | 0.610 |
| SO_0859 | barA | SO_0859 | SO_3457 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.991 |
| SO_0859 | torS | SO_0859 | SO_1230 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.989 |
| SO_0859 | ttrR | SO_0859 | SO_4157 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two-component system, LuxR family, response regulator TtrR; Thiosulfate/tetrathionate-responsive two component signal transduction system response regulator TtrR. | 0.693 |
| SO_0859 | ttrS | SO_0859 | SO_4155 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Thiosulfate/tetrathionate-responsive two component signal transduction system histidine kinase TtrS. | 0.683 |
| SO_1416 | SO_0859 | SO_1416 | SO_0859 | Two component signal transduction system response regulator LuxR family. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.688 |
| SO_1416 | SO_4002 | SO_1416 | SO_4002 | Two component signal transduction system response regulator LuxR family. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.651 |
| SO_1416 | barA | SO_1416 | SO_3457 | Two component signal transduction system response regulator LuxR family. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.595 |
| SO_1416 | torS | SO_1416 | SO_1230 | Two component signal transduction system response regulator LuxR family. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.636 |
| SO_1416 | ttrS | SO_1416 | SO_4155 | Two component signal transduction system response regulator LuxR family. | Thiosulfate/tetrathionate-responsive two component signal transduction system histidine kinase TtrS. | 0.852 |
| SO_4002 | SO_0859 | SO_4002 | SO_0859 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.991 |
| SO_4002 | SO_1416 | SO_4002 | SO_1416 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator LuxR family. | 0.651 |