| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0490 | SO_4623 | SO_0490 | SO_4623 | Transmembrane transcriptional regulator CadC family. | Two component signal transduction system response regulator. | 0.571 |
| SO_0490 | ccmB | SO_0490 | SO_0262 | Transmembrane transcriptional regulator CadC family. | ABC-type heme export system permease component 1 CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. | 0.652 |
| SO_0490 | ttrR | SO_0490 | SO_4157 | Transmembrane transcriptional regulator CadC family. | Two-component system, LuxR family, response regulator TtrR; Thiosulfate/tetrathionate-responsive two component signal transduction system response regulator TtrR. | 0.720 |
| SO_0490 | ttrS | SO_0490 | SO_4155 | Transmembrane transcriptional regulator CadC family. | Thiosulfate/tetrathionate-responsive two component signal transduction system histidine kinase TtrS. | 0.720 |
| SO_0859 | SO_1417 | SO_0859 | SO_1417 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system histidine kinase. | 0.779 |
| SO_0859 | SO_4002 | SO_0859 | SO_4002 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.991 |
| SO_0859 | SO_4623 | SO_0859 | SO_4623 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator. | 0.927 |
| SO_0859 | cheR-3 | SO_0859 | SO_3251 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Chemotaxis signal transduction system MCP methyltransferase CheR. | 0.556 |
| SO_0859 | prlS | SO_0859 | SO_2742 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Proline-responsive two component signal transduction system hybrid histidine kinase/resposne regulator PrlS. | 0.986 |
| SO_0859 | torS | SO_0859 | SO_1230 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.989 |
| SO_0859 | ttrR | SO_0859 | SO_4157 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two-component system, LuxR family, response regulator TtrR; Thiosulfate/tetrathionate-responsive two component signal transduction system response regulator TtrR. | 0.693 |
| SO_0859 | ttrS | SO_0859 | SO_4155 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Thiosulfate/tetrathionate-responsive two component signal transduction system histidine kinase TtrS. | 0.683 |
| SO_1417 | SO_0859 | SO_1417 | SO_0859 | Two component signal transduction system histidine kinase. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.779 |
| SO_1417 | SO_4002 | SO_1417 | SO_4002 | Two component signal transduction system histidine kinase. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.798 |
| SO_1417 | SO_4623 | SO_1417 | SO_4623 | Two component signal transduction system histidine kinase. | Two component signal transduction system response regulator. | 0.429 |
| SO_1417 | prlS | SO_1417 | SO_2742 | Two component signal transduction system histidine kinase. | Proline-responsive two component signal transduction system hybrid histidine kinase/resposne regulator PrlS. | 0.612 |
| SO_1417 | torS | SO_1417 | SO_1230 | Two component signal transduction system histidine kinase. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.698 |
| SO_1417 | ttrR | SO_1417 | SO_4157 | Two component signal transduction system histidine kinase. | Two-component system, LuxR family, response regulator TtrR; Thiosulfate/tetrathionate-responsive two component signal transduction system response regulator TtrR. | 0.832 |
| SO_4002 | SO_0859 | SO_4002 | SO_0859 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.991 |
| SO_4002 | SO_1417 | SO_4002 | SO_1417 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system histidine kinase. | 0.798 |