STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prrBTwo-component system, sensor histidine kinase RegB; Oxygen-responsive two component signal transduction system controlling redox affected systems histidine kinase PrrB. (427 aa)    
Predicted Functional Partners:
prrA
Two-component system, response regulator RegA; Oxygen-responsive two component signal transduction system controlling redox affected systems response regulator PrrA.
 0.999
SO_4002
Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain.
  
 
 0.960
barA
Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA.
  
 
 0.937
SO_0859
Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain.
  
 
 0.860
SO_4174
dTDP-4-dehydrorhamnose reductase family; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.
  
    0.782
SO_2127
Diguanylate cyclase with response regulator receiver modulation.
  
 
 0.778
atpC
ATP synthase F1 epsilon subunit AtpC; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.723
atpH
ATP synthase F1 delta subunit AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.
      
 0.718
SO_4171
Uncharacterized protein.
  
    0.683
phoR
Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Phosphate-responsive two component signal transduction system histidine kinase with PAS and DUF3329 domains PhoR.
   
 
 0.651
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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