Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mxdADiguanylate cyclase-like protein MxdA. (462 aa)    
Predicted Functional Partners:
mxdB
Glycosyl transferase family 2 MxdB.
 
  
 0.998
mxdC
Membrane anchored protein MxdC.
     
 0.963
SO_4002
Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain.
  
 
 0.899
mxdD
Periplasmic protein of expolysaccharide biosynthesis cluster MxdD.
  
  
 0.888
SO_0859
Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain.
  
 
 0.836
cheY-3
Chemotaxis signal transduction system response regulator CheY.
   
 
 0.796
SO_4407
Diguanylate cyclase.
   
  
 0.710
SO_2889
Two component signal transduction system histidine kinase with Cache_1 and PAS sensory domains.
   
 
 0.692
SO_1712
Transcriptional regulator.
  
     0.672
SO_2290
Rhodanese domain protein UPF0176 family; Belongs to the UPF0176 family.
      
 0.670
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (28%) [HD]