node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SO_2535 | folE | SO_2535 | SO_4254 | Glutamine amidotransferase class II. | GTP cyclohydrolase I FolE. | 0.918 |
SO_2535 | queC | SO_2535 | SO_2503 | Glutamine amidotransferase class II. | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.922 |
SO_2535 | queD | SO_2535 | SO_2179 | Glutamine amidotransferase class II. | Queosine biosynthesis protein QueD. | 0.922 |
folB | folE | SO_1291 | SO_4254 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I FolE. | 0.916 |
folB | folK | SO_1291 | SO_0871 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. | 0.986 |
folB | folP | SO_1291 | SO_1198 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.992 |
folB | phoD | SO_1291 | SO_0806 | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Ca(2+)-dependent phospholipase D PhoD. | 0.909 |
folE | SO_2535 | SO_4254 | SO_2535 | GTP cyclohydrolase I FolE. | Glutamine amidotransferase class II. | 0.918 |
folE | folB | SO_4254 | SO_1291 | GTP cyclohydrolase I FolE. | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.916 |
folE | folK | SO_4254 | SO_0871 | GTP cyclohydrolase I FolE. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. | 0.993 |
folE | folP | SO_4254 | SO_1198 | GTP cyclohydrolase I FolE. | Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.983 |
folE | folX | SO_4254 | SO_2921 | GTP cyclohydrolase I FolE. | D-erythro-78-dihydroneopterin triphosphate epimerase FolX. | 0.987 |
folE | phoD | SO_4254 | SO_0806 | GTP cyclohydrolase I FolE. | Ca(2+)-dependent phospholipase D PhoD. | 0.920 |
folE | queC | SO_4254 | SO_2503 | GTP cyclohydrolase I FolE. | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.950 |
folE | queD | SO_4254 | SO_2179 | GTP cyclohydrolase I FolE. | Queosine biosynthesis protein QueD. | 0.986 |
folE | ribA | SO_4254 | SO_2831 | GTP cyclohydrolase I FolE. | GTP cyclohydrolase II RibA; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.967 |
folE | ribBA | SO_4254 | SO_3467 | GTP cyclohydrolase I FolE. | Bifunctional 34-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.938 |
folK | folB | SO_0871 | SO_1291 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.986 |
folK | folE | SO_0871 | SO_4254 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. | GTP cyclohydrolase I FolE. | 0.993 |
folK | folP | SO_0871 | SO_1198 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. | Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |