| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0381 | hsdM-2 | SO_0381 | SO_4265 | Type I RM locus Fic family protein. | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | 0.735 |
| SO_0381 | hsdR | SO_0381 | SO_0380 | Type I RM locus Fic family protein. | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.885 |
| SO_0381 | hsdS | SO_0381 | SO_0382 | Type I RM locus Fic family protein. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.882 |
| SO_0381 | hsdS-3 | SO_0381 | SO_4264 | Type I RM locus Fic family protein. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.698 |
| SO_0381 | mloA | SO_0381 | SO_4266 | Type I RM locus Fic family protein. | Fic family protein MloA; Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. | 0.483 |
| hsdM-2 | SO_0381 | SO_4265 | SO_0381 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Type I RM locus Fic family protein. | 0.735 |
| hsdM-2 | hsdR | SO_4265 | SO_0380 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.951 |
| hsdM-2 | hsdR-2 | SO_4265 | SO_4267 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR. | 0.952 |
| hsdM-2 | hsdS | SO_4265 | SO_0382 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.973 |
| hsdM-2 | hsdS-2 | SO_4265 | SO_1460 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.972 |
| hsdM-2 | hsdS-3 | SO_4265 | SO_4264 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.999 |
| hsdM-2 | mloA | SO_4265 | SO_4266 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Fic family protein MloA; Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. | 0.596 |
| hsdM-2 | potG | SO_4265 | SO_1271 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | ABC-type putrescine uptake system ATPase component PotG; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. | 0.802 |
| hsdM-2 | rflA | SO_4265 | SO_4263 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Phage P1-related protein in restrction modification operon RflA. | 0.778 |
| hsdM-2 | rflB | SO_4265 | SO_4262 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Phage P1-related protein in restrction modification operon RflB. | 0.776 |
| hsdR | SO_0381 | SO_0380 | SO_0381 | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I RM locus Fic family protein. | 0.885 |
| hsdR | hsdM-2 | SO_0380 | SO_4265 | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | 0.951 |
| hsdR | hsdR-2 | SO_0380 | SO_4267 | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR. | 0.602 |
| hsdR | hsdS | SO_0380 | SO_0382 | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.965 |
| hsdR | hsdS-3 | SO_0380 | SO_4264 | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.928 |