| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0381 | hsdM-2 | SO_0381 | SO_4265 | Type I RM locus Fic family protein. | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | 0.697 |
| SO_0381 | hsdR | SO_0381 | SO_0380 | Type I RM locus Fic family protein. | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.851 |
| SO_0381 | hsdS | SO_0381 | SO_0382 | Type I RM locus Fic family protein. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.869 |
| SO_0381 | hsdS-3 | SO_0381 | SO_4264 | Type I RM locus Fic family protein. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.670 |
| hsdM-2 | SO_0381 | SO_4265 | SO_0381 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Type I RM locus Fic family protein. | 0.697 |
| hsdM-2 | hsdR | SO_4265 | SO_0380 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | 0.972 |
| hsdM-2 | hsdR-2 | SO_4265 | SO_4267 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR. | 0.949 |
| hsdM-2 | hsdS | SO_4265 | SO_0382 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.970 |
| hsdM-2 | hsdS-3 | SO_4265 | SO_4264 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.994 |
| hsdM-2 | mdtL | SO_4265 | SO_4021 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Chloramphenicol resistance protein MdtL. | 0.708 |
| hsdM-2 | potG | SO_4265 | SO_1271 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | ABC-type putrescine uptake system ATPase component PotG; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. | 0.831 |
| hsdM-2 | rflA | SO_4265 | SO_4263 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Phage P1-related protein in restrction modification operon RflA. | 0.779 |
| hsdM-2 | rflB | SO_4265 | SO_4262 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Phage P1-related protein in restrction modification operon RflB. | 0.779 |
| hsdM-2 | tpmT | SO_4265 | SO_0582 | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | Thiopurine S-methyltransferase TpmT; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. | 0.801 |
| hsdR | SO_0381 | SO_0380 | SO_0381 | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I RM locus Fic family protein. | 0.851 |
| hsdR | hsdM-2 | SO_0380 | SO_4265 | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | 0.972 |
| hsdR | hsdR-2 | SO_0380 | SO_4267 | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR. | 0.638 |
| hsdR | hsdS | SO_0380 | SO_0382 | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.973 |
| hsdR | hsdS-3 | SO_0380 | SO_4264 | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification. | Type I restriction-modification system restriction endonuclease DNA specificity subunit HsdS. | 0.952 |
| hsdR-2 | hsdM-2 | SO_4267 | SO_4265 | Type I restriction-modification system restriction endonuclease cleavage subunit HsdR. | Type I restriction-modification system N6-adenine DNA methyltransferase HsdM. | 0.949 |