| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0859 | SO_4002 | SO_0859 | SO_4002 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.995 |
| SO_0859 | SO_4465 | SO_0859 | SO_4465 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Protein of unknown function DUF323. | 0.449 |
| SO_0859 | gltB | SO_0859 | SO_1325 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | NADPH-dependent glutamate synthase large subunit GltB. | 0.661 |
| SO_0859 | macB | SO_0859 | SO_0821 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.515 |
| SO_1068 | SO_4465 | SO_1068 | SO_4465 | 4-hydroxybenzoyl-CoA thioesterase family protein. | Protein of unknown function DUF323. | 0.434 |
| SO_2535 | SO_4465 | SO_2535 | SO_4465 | Glutamine amidotransferase class II. | Protein of unknown function DUF323. | 0.467 |
| SO_4002 | SO_0859 | SO_4002 | SO_0859 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.995 |
| SO_4002 | SO_4465 | SO_4002 | SO_4465 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Protein of unknown function DUF323. | 0.463 |
| SO_4002 | gltB | SO_4002 | SO_1325 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | NADPH-dependent glutamate synthase large subunit GltB. | 0.625 |
| SO_4002 | macB | SO_4002 | SO_0821 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.646 |
| SO_4463 | SO_4465 | SO_4463 | SO_4465 | 2OG-Fe(II) oxygenase family protein. | Protein of unknown function DUF323. | 0.410 |
| SO_4465 | SO_0859 | SO_4465 | SO_0859 | Protein of unknown function DUF323. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.449 |
| SO_4465 | SO_1068 | SO_4465 | SO_1068 | Protein of unknown function DUF323. | 4-hydroxybenzoyl-CoA thioesterase family protein. | 0.434 |
| SO_4465 | SO_2535 | SO_4465 | SO_2535 | Protein of unknown function DUF323. | Glutamine amidotransferase class II. | 0.467 |
| SO_4465 | SO_4002 | SO_4465 | SO_4002 | Protein of unknown function DUF323. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.463 |
| SO_4465 | SO_4463 | SO_4465 | SO_4463 | Protein of unknown function DUF323. | 2OG-Fe(II) oxygenase family protein. | 0.410 |
| SO_4465 | gltB | SO_4465 | SO_1325 | Protein of unknown function DUF323. | NADPH-dependent glutamate synthase large subunit GltB. | 0.459 |
| SO_4465 | macB | SO_4465 | SO_0821 | Protein of unknown function DUF323. | ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.480 |
| SO_4465 | nrfJ | SO_4465 | SO_3325 | Protein of unknown function DUF323. | Periplasmic protein of unknown function NrfJ. | 0.403 |
| SO_4465 | pubA | SO_4465 | SO_3030 | Protein of unknown function DUF323. | Putrescine monooxygenase PubA. | 0.451 |