STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppnPProtein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (103 aa)    
Predicted Functional Partners:
yrfG
HAD-superfamily hydrolase subfamily IA variant 3 protein family YrfG.
  
 
  0.917
ushA
Bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA; Belongs to the 5'-nucleotidase family.
  
  
  0.913
yfbR
5' nucleotidase YfbR; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.
  
 
  0.913
deoA
Thymidine phosphorylase DeoA; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
     
 0.910
udp
Uridine phosphorylase Udp; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
     
 0.908
nadP
N-ribosylnicotinamide phosphorylase NadP.
     
 0.908
add
Adenosine deaminase Add; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
     
 0.901
deoD
Purine nucleoside phosphorylase DeoD.
     
  0.900
yjjG
5' nucleotide phosphatase YjjG.
     
  0.900
deoD-2
Purine nucleoside phosphorylase DeoD.
     
  0.900
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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