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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpxAPeriplasmic stress-responsive two component signal transduction system histidine kinase CpxA. (449 aa)    
Predicted Functional Partners:
cpxR
Periplasmic stress-responsive two component signal transduction system response regulator CpxR.
 0.999
SO_4002
Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain.
 
 
0.967
rstA
Two component signal transduction system controlling curli production response regulator RstA.
 
 0.960
kdpE
Two-component system, OmpR family, KDP operon response regulator KdpE; Two component signal transduction system controlling the osmosenstive K+ channel response regulator KdpE.
 
 0.949
barA
Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA.
 
 
0.948
ompR
Osmolarity-responsive two component signal transduction system response regulator OmpR.
 
 0.947
phoB
Phosphate-responsive two component signal transduction system response regulator PhoB.
 
 0.907
SO_2426
Two component signal transduction system response regulator.
 
 0.889
SO_0859
Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain.
 
 
0.882
qseB
AI-3-responsive two component signal transduction system response regulator QseB.
 
 0.866
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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