Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fdhD-2Formate dehydrogenase assembly/maturation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (298 aa)    
Predicted Functional Partners:
SO_4506
Iron-sulfur cluster-binding protein.
 
  
 0.945
fdhA
Formate dehydrogenase molybdopterin-binding subunit FdhA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.936
mobA
Tungstopterin-guanine dinucleotide biosynthesis protein A MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
 
 
 0.923
SO_4502
Molydopterin cofactor biosynthesis protein.
 
  
 0.917
fdhE
Nitrate-inducible formate dehydrogenase chaperone FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
     
 0.888
fdhA-2
Fnr-inducilble formate dehydrogenase molybdopterin-binding subunit FdhA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 
 0.856
fdhT
Formate dehydrogenase chaperone FdhT.
 
  
 0.838
SO_4505
Formate dehydrogenase associated protein of unknown function DUF3506.
 
     0.832
fdhC
Formate dehydrogenase cytochrome b subunit FdhC.
 
  
 0.823
tupA
ABC-type tungstate uptake system substrate-binding component TupA.
 
     0.780
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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