close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fdhAFormate dehydrogenase molybdopterin-binding subunit FdhA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (949 aa)    
Predicted Functional Partners:
fdhC
Formate dehydrogenase cytochrome b subunit FdhC.
 
 
 0.989
SO_4506
Iron-sulfur cluster-binding protein.
 
  
 0.977
fdhB
Formate dehydrogenase FeS subunit FdhB.
 
 
 0.971
fdhC-2
Fnr-inducible formate dehydrogenase cytochrome b subunit FdhC.
 
 
 0.967
napB
Periplasmic nitrate reductase cytochrome c subunit NapB; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type CymA protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Not essential for nitrate reduction but confers advantage to the organism when grown on nitrate and thereby a fitness gain in utilizing nitrate. Belongs to the NapB family.
  
 0.943
fdhD-2
Formate dehydrogenase assembly/maturation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
 0.935
fdhB-2
Fnr-inducible formate dehydrogenase FeS subunit FdhB.
 
 
 0.930
fdhT
Formate dehydrogenase chaperone FdhT.
 
 
 0.911
purU
Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
  
 
  0.903
frmB
S-formylglutathione hydrolase FrmB; Serine hydrolase involved in the detoxification of formaldehyde.
   
 
  0.900
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.