Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
SO_4539Extracellular peptidase family S8; Belongs to the peptidase S8 family. (1634 aa)    
Predicted Functional Partners:
SO_0497
Serine/threonine protein kinase.
 
 
 0.803
SO_0404
Zinc dependent metalloprotease domain lipoprotein.
  
     0.739
hipA
Toxin-antitoxin system toxin HipA family; Toxic component of a type II toxin-antitoxin (TA) system; overexpression in wild-type temporarily inhibits cell growth, overexpression in a hipAB deletion leads to acute growth inhibition. The toxic effect of HipA is neutralized by its cognate antitoxin HipB. In the ternary phosphoserine-HipA-HipB-DNA complex the DNA is bent about 125 degrees; all HipA in the crystallized ternary complex is phosphorylated. In E.coli phosphorylation of HipA is thought to release HipB from the HipA-HipB-DNA complex, suggesting the complex functions differently in [...]
  
    0.729
SO_0939
Split-soret diheme cytochrome c.
  
     0.691
SO_3124
Dual specificity protein-tyrosine phosphatase.
  
    0.691
mtrB
Extracellular iron oxide respiratory system outer membrane component MtrB.
  
     0.641
SO_1505
Proton:peptide symporter POT family.
  
   
 0.632
SO_0757
TPR domain lipoprotein.
 
    0.628
SO_2902
RDD domain protein.
  
    0.604
SO_2934
Extracellular lipase Pla-1/cef family.
  
     0.544
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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