STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cusFCopper efflux pump periplasmic metallochaperone CusF. (86 aa)    
Predicted Functional Partners:
cusB
Copper/silver efflux pump MFP component CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
    0.965
macB
ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.908
cusA
Copper/silver efflux pump permease component CusA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.898
SO_0520
Heavy metal efflux pump permease component CzcA family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.893
pstC
ABC-type high affinity phosphate uptake system permease component PstC.
      
 0.734
pstB2
ABC-type phosphate uptake system permease ATPase component PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
      
 0.713
pstA-2
ABC-type phosphate uptake system permease component PstA.
      
 0.713
pstS
ABC-type phosphate uptake system substrate-binding component PstS.
      
 0.712
pstB
ABC-type high affinity phosphate uptake system ATPase component PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
      
 0.659
SO_4593
Periplasmic protein of unknown function DUF2057.
  
    0.602
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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