Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
dinFDNA damage-inducible multidrug and toxin efflux protein DinF. (455 aa)    
Predicted Functional Partners:
SO_4616
Carbohydrate esterase family 4.
 
     0.722
SO_4618
Subfamily S9C unassigned peptidase.
       0.558
rpsA
Ribosomal protein S1 RpsA; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
   
    0.509
norM
drug:Na+ antiporter NorM; Multidrug efflux pump; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
      
 0.486
ybbP
Putative ABC-type fatty acid export system permease component YbbP.
      
 0.480
mexE
HAE1 family efflux pump MFP component MexE; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
   
  
 0.478
vexR
Transcriptional repressor of multidrug/detergent efflux pump VexR.
      
 0.478
SO_0002
Glutathione uptake transporter.
    
 
 0.465
lexA
Bifunctional transcriptional repressor of SOS-response/self-cleaving protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.459
tolC
Global secretion system secretin TolC.
      
 0.443
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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