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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
urdAFAD-dependent oxidoreductase; Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino- histidine). The physiological electron donor is unknown; it might be the membrane-bound tetraheme cytochrome c (CymA). Enables anaerobic growth with urocanate as a sole terminal electron acceptor, and thus can provide the cells with a niche where no other bacteria can compete and survive. Is unable to reduce cinnamate and other unsaturated organic acids such as acrylic, crotonic, fumaric and orotic acids. Has no fumarate reductase or succinate [...] (582 aa)    
Predicted Functional Partners:
nuoCD
NADH-ubiquinone oxidoreductase subunit CD NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.960
SO_3057
Phenylalanine/histidine ammonia-lyase family protein.
   
 
  0.905
hutU
Urocanate hydratase HutU; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
     
 0.903
hutH
Histidine ammonia-lyase HutH; Belongs to the PAL/histidase family.
   
 
  0.902
SO_4374
Phenylalanine/tyrosine ammonia-lyase.
   
 
  0.902
sdhB
Succinate dehydrogenase iron-sulfur protein SdhB; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.887
frdB
Quinol:fumarate reductase FeS subunit FrdB.
 
 0.881
SO_4506
Iron-sulfur cluster-binding protein.
  
 
 0.855
apbE
Fe-S assembly/repair lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.
 
  
 0.847
sye3
NAD(P)H:flavin oxidoreductase Sye3.
 
    0.838
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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