Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SO_4624Transcriptional regulator LuxR family. (248 aa)    
Predicted Functional Partners:
SO_4622
Two component signal transduction system histidine kinase.
  
  
 0.798
SO_4623
Two component signal transduction system response regulator.
  
  
 0.773
macB
ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
   
    0.602
barA
Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA.
      
 0.546
SO_4002
Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain.
      
 0.546
SO_4625
Predicted phosphoribosyltransferase ComF family.
  
    0.539
SO_0859
Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain.
      
 0.503
SO_4621
Nucleoside-specifc outer membrane porin Tsx family.
  
    0.474
SO_0387
Uncharacterized protein.
   
    0.429
urdA
FAD-dependent oxidoreductase; Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino- histidine). The physiological electron donor is unknown; it might be the membrane-bound tetraheme cytochrome c (CymA). Enables anaerobic growth with urocanate as a sole terminal electron acceptor, and thus can provide the cells with a niche where no other bacteria can compete and survive. Is unable to reduce cinnamate and other unsaturated organic acids such as acrylic, crotonic, fumaric and orotic acids. Has no fumarate reductase or succinate [...]
  
  
 0.402
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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