| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0859 | SO_4002 | SO_0859 | SO_4002 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.995 |
| SO_0859 | barA | SO_0859 | SO_3457 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.995 |
| SO_0859 | cpxA | SO_0859 | SO_4478 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Periplasmic stress-responsive two component signal transduction system histidine kinase CpxA. | 0.812 |
| SO_0859 | envZ | SO_0859 | SO_4634 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Osmolarity-responsive two component signal transduction system histidine kinase EnvZ. | 0.776 |
| SO_0859 | ompR | SO_0859 | SO_4633 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Osmolarity-responsive two component signal transduction system response regulator OmpR. | 0.875 |
| SO_0859 | phoQ | SO_0859 | SO_1945 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system histidine kinase PhoQ. | 0.776 |
| SO_0859 | phoR | SO_0859 | SO_1559 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Phosphate-responsive two component signal transduction system histidine kinase with PAS and DUF3329 domains PhoR. | 0.781 |
| SO_0859 | rstB | SO_0859 | SO_3595 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system histidine kinase RstB. | 0.776 |
| SO_0859 | torS | SO_0859 | SO_1230 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.993 |
| SO_4002 | SO_0859 | SO_4002 | SO_0859 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.995 |
| SO_4002 | barA | SO_4002 | SO_3457 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.995 |
| SO_4002 | cpxA | SO_4002 | SO_4478 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Periplasmic stress-responsive two component signal transduction system histidine kinase CpxA. | 0.901 |
| SO_4002 | envZ | SO_4002 | SO_4634 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Osmolarity-responsive two component signal transduction system histidine kinase EnvZ. | 0.892 |
| SO_4002 | ompR | SO_4002 | SO_4633 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Osmolarity-responsive two component signal transduction system response regulator OmpR. | 0.770 |
| SO_4002 | phoQ | SO_4002 | SO_1945 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system histidine kinase PhoQ. | 0.878 |
| SO_4002 | phoR | SO_4002 | SO_1559 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Phosphate-responsive two component signal transduction system histidine kinase with PAS and DUF3329 domains PhoR. | 0.767 |
| SO_4002 | rstB | SO_4002 | SO_3595 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system histidine kinase RstB. | 0.901 |
| SO_4002 | torS | SO_4002 | SO_1230 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.993 |
| SO_4635 | envZ | SO_4635 | SO_4634 | Chemotaxis signal transduction system methyl accepting sensory transducer. | Osmolarity-responsive two component signal transduction system histidine kinase EnvZ. | 0.889 |
| SO_4635 | ompR | SO_4635 | SO_4633 | Chemotaxis signal transduction system methyl accepting sensory transducer. | Osmolarity-responsive two component signal transduction system response regulator OmpR. | 0.809 |