| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0859 | SO_4002 | SO_0859 | SO_4002 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.995 |
| SO_0859 | arcA | SO_0859 | SO_3988 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system controlling aerobic respiration response regulator ArcA. | 0.878 |
| SO_0859 | barA | SO_0859 | SO_3457 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.995 |
| SO_0859 | cpxR | SO_0859 | SO_4477 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Periplasmic stress-responsive two component signal transduction system response regulator CpxR. | 0.857 |
| SO_0859 | envZ | SO_0859 | SO_4634 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Osmolarity-responsive two component signal transduction system histidine kinase EnvZ. | 0.776 |
| SO_0859 | ompR | SO_0859 | SO_4633 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Osmolarity-responsive two component signal transduction system response regulator OmpR. | 0.875 |
| SO_0859 | phoB | SO_0859 | SO_1558 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Phosphate-responsive two component signal transduction system response regulator PhoB. | 0.857 |
| SO_0859 | phoP | SO_0859 | SO_1946 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator PhoP. | 0.880 |
| SO_0859 | torR | SO_0859 | SO_1228 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | TMAO-responsive two component signal transduction system response regulator TorR. | 0.886 |
| SO_4002 | SO_0859 | SO_4002 | SO_0859 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.995 |
| SO_4002 | arcA | SO_4002 | SO_3988 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system controlling aerobic respiration response regulator ArcA. | 0.823 |
| SO_4002 | barA | SO_4002 | SO_3457 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.995 |
| SO_4002 | cpxR | SO_4002 | SO_4477 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Periplasmic stress-responsive two component signal transduction system response regulator CpxR. | 0.804 |
| SO_4002 | envZ | SO_4002 | SO_4634 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Osmolarity-responsive two component signal transduction system histidine kinase EnvZ. | 0.892 |
| SO_4002 | ompR | SO_4002 | SO_4633 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Osmolarity-responsive two component signal transduction system response regulator OmpR. | 0.770 |
| SO_4002 | phoB | SO_4002 | SO_1558 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Phosphate-responsive two component signal transduction system response regulator PhoB. | 0.798 |
| SO_4002 | phoP | SO_4002 | SO_1946 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator PhoP. | 0.821 |
| SO_4002 | torR | SO_4002 | SO_1228 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | TMAO-responsive two component signal transduction system response regulator TorR. | 0.844 |
| SO_4635 | envZ | SO_4635 | SO_4634 | Chemotaxis signal transduction system methyl accepting sensory transducer. | Osmolarity-responsive two component signal transduction system histidine kinase EnvZ. | 0.889 |
| SO_4635 | ompR | SO_4635 | SO_4633 | Chemotaxis signal transduction system methyl accepting sensory transducer. | Osmolarity-responsive two component signal transduction system response regulator OmpR. | 0.809 |