Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
vmeAProton-coupled multidrug efflux pump MFP component VmeA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (382 aa)    
Predicted Functional Partners:
vmeB
Proton-coupled multidrug efflux pump permease component VmeB.
 0.995
macC
ABC-type macrolide export system secretin component MacC.
 
 0.970
SO_4014
HAE1 family effllux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.929
SO_1882
HAE1 family efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 0.913
vexA
RND-type multidrug/detergent efflux system permease component VexA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.912
tolC
Global secretion system secretin TolC.
 
 0.904
SO_3484
HAE1 family efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 0.902
oleA
Polyolefin biosynthetic pathway thiolase OleA; Involved in olefin biosynthesis. Catalyzes a non-decarboxylative head-to-head Claisen condensation of two acyl-CoA molecules, generating an (R)-2-alkyl-3-oxoalkanoate (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28- hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature.
   
  
 0.875
SO_1924
RND superfamily efflux pump permease component 2; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.874
SO_3103
Thiophosphate efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
 0.874
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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