| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ccoN | ccoO | SO_2364 | SO_2363 | Cbb3-type cytochrome c oxidase subunit I CcoN; Belongs to the heme-copper respiratory oxidase family. | Cbb3-type cytochrome c oxidase subunit II CcoO. | 0.999 |
| ccoN | hemN | SO_2364 | SO_4730 | Cbb3-type cytochrome c oxidase subunit I CcoN; Belongs to the heme-copper respiratory oxidase family. | Coproporphyrinogen III oxidase oxygen-independent HemN; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.840 |
| ccoN | ompW | SO_2364 | SO_1673 | Cbb3-type cytochrome c oxidase subunit I CcoN; Belongs to the heme-copper respiratory oxidase family. | Outer membrane protein OmpW. | 0.752 |
| ccoO | ccoN | SO_2363 | SO_2364 | Cbb3-type cytochrome c oxidase subunit II CcoO. | Cbb3-type cytochrome c oxidase subunit I CcoN; Belongs to the heme-copper respiratory oxidase family. | 0.999 |
| ccoO | hemN | SO_2363 | SO_4730 | Cbb3-type cytochrome c oxidase subunit II CcoO. | Coproporphyrinogen III oxidase oxygen-independent HemN; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.808 |
| ccoO | ompW | SO_2363 | SO_1673 | Cbb3-type cytochrome c oxidase subunit II CcoO. | Outer membrane protein OmpW. | 0.827 |
| hemA | hemE | SO_3834 | SO_0435 | glutamyl-tRNA reductase HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.925 |
| hemA | hemF | SO_3834 | SO_0038 | glutamyl-tRNA reductase HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Aerobic coproporphyrinogen III oxidase HemF; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.878 |
| hemA | hemG | SO_3834 | SO_0025 | glutamyl-tRNA reductase HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Oxygen-independent protoporphyrinogen oxidase HemG. | 0.684 |
| hemA | hemG-2 | SO_3834 | SO_0027 | glutamyl-tRNA reductase HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Oxygen-independent protoporphyrinogen oxidase HemG. | 0.812 |
| hemA | hemG-3 | SO_3834 | SO_3720 | glutamyl-tRNA reductase HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Oxygen-independent protoporphyrinogen oxidase HemG. | 0.685 |
| hemA | hemH | SO_3834 | SO_2019 | glutamyl-tRNA reductase HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Ferrochelatase HemH; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.871 |
| hemA | hemN | SO_3834 | SO_4730 | glutamyl-tRNA reductase HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | Coproporphyrinogen III oxidase oxygen-independent HemN; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.820 |
| hemE | hemA | SO_0435 | SO_3834 | Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | glutamyl-tRNA reductase HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.925 |
| hemE | hemF | SO_0435 | SO_0038 | Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Aerobic coproporphyrinogen III oxidase HemF; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.978 |
| hemE | hemG | SO_0435 | SO_0025 | Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Oxygen-independent protoporphyrinogen oxidase HemG. | 0.502 |
| hemE | hemG-2 | SO_0435 | SO_0027 | Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Oxygen-independent protoporphyrinogen oxidase HemG. | 0.462 |
| hemE | hemG-3 | SO_0435 | SO_3720 | Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Oxygen-independent protoporphyrinogen oxidase HemG. | 0.504 |
| hemE | hemH | SO_0435 | SO_2019 | Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Ferrochelatase HemH; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.939 |
| hemE | hemN | SO_0435 | SO_4730 | Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Coproporphyrinogen III oxidase oxygen-independent HemN; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.974 |