| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carB | glmS | SO_1142 | SO_4741 | Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family. | Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.942 |
| carB | glnA | SO_1142 | SO_4410 | Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family. | Glutamine synthetase GlnA. | 0.926 |
| carB | gltB | SO_1142 | SO_1325 | Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family. | NADPH-dependent glutamate synthase large subunit GltB. | 0.974 |
| carB | nagB | SO_1142 | SO_3506 | Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family. | Glucosamine-6-phosphate deaminase NagB. | 0.900 |
| carB | purF | SO_1142 | SO_3064 | Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family. | Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.992 |
| carB | puuA | SO_1142 | SO_1268 | Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family. | Gamma-glutamyl-putrescine synthase PuuA; Belongs to the glutamine synthetase family. | 0.926 |
| glmM | glmS | SO_1199 | SO_4741 | Phosphoglucosamine mutase GlmM; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.979 |
| glmM | glmU | SO_1199 | SO_4745 | Phosphoglucosamine mutase GlmM; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.998 |
| glmM | nagA | SO_1199 | SO_3505 | Phosphoglucosamine mutase GlmM; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | N-acetylglucosamine-6-phosphate deacetylase NagA; Belongs to the metallo-dependent hydrolases superfamily. NagA family. | 0.917 |
| glmM | nagB | SO_1199 | SO_3506 | Phosphoglucosamine mutase GlmM; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-6-phosphate deaminase NagB. | 0.906 |
| glmM | pgi | SO_1199 | SO_3547 | Phosphoglucosamine mutase GlmM; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucose-6-phosphate isomerase Pgi. | 0.416 |
| glmS | carB | SO_4741 | SO_1142 | Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase large subunit CarB; Belongs to the CarB family. | 0.942 |
| glmS | glmM | SO_4741 | SO_1199 | Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase GlmM; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.979 |
| glmS | glmU | SO_4741 | SO_4745 | Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.977 |
| glmS | glnA | SO_4741 | SO_4410 | Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glutamine synthetase GlnA. | 0.932 |
| glmS | gltB | SO_4741 | SO_1325 | Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | NADPH-dependent glutamate synthase large subunit GltB. | 0.967 |
| glmS | nagA | SO_4741 | SO_3505 | Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | N-acetylglucosamine-6-phosphate deacetylase NagA; Belongs to the metallo-dependent hydrolases superfamily. NagA family. | 0.931 |
| glmS | nagB | SO_4741 | SO_3506 | Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucosamine-6-phosphate deaminase NagB. | 0.945 |
| glmS | pgi | SO_4741 | SO_3547 | Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucose-6-phosphate isomerase Pgi. | 0.929 |
| glmS | purF | SO_4741 | SO_3064 | Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.921 |