close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alpAMu phage lytic protein AlpA. (70 aa)    
Predicted Functional Partners:
xis
Lambda phage DNA excisionase Xis.
      
 0.878
SO_3146
DNA-binding protein H-NS family; Belongs to the histone-like protein H-NS family.
      
 0.740
intA
CP4-57-like prophage integrase IntA; Belongs to the 'phage' integrase family.
  
  
 0.727
SO_1442
Uncharacterized protein.
       0.667
SO_1440
Bifunctional toxin-antitoxin system HepN family antidote fused to MNT family toxin.
     
 0.525
SO_1441
Putative cytoplasmic protein.
       0.504
yheT
Peptidase S33 family YheT.
      
 0.485
cspA
Cold shock protein CspA.
   
  
 0.470
parE
DNA topoisomerase IV B subunit ParE; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
      
 0.457
rumA
23S rRNA (uracil1939-C5)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
      
 0.454
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (24%) [HD]