Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TWNKTwinkle mtDNA helicase. (762 aa)    
Predicted Functional Partners:
POLG
DNA polymerase gamma, catalytic subunit.
   
 
 0.962
POLG2
DNA polymerase gamma 2, accessory subunit.
     
 0.938
ENSANIP00000002051
annotation not available
    
   0.925
POLRMT
RNA polymerase mitochondrial.
   
 
 0.899
SSBP1
Single stranded DNA binding protein 1.
   
 
 0.891
PTGES2
Prostaglandin E synthase 2.
    
   0.880
NUBPL
Nucleotide binding protein like.
    
 
 0.858
ENSANIP00000020554
annotation not available
    
 
 0.858
TFAM
Transcription factor A, mitochondrial.
     
 0.845
PDIA3
Protein disulfide isomerase family A member 3.
    
   0.830
Your Current Organism:
Accipiter nisus
NCBI taxonomy Id: 211598
Other names: A. nisus, Eurasian sparrowhawk
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