STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CFLARCASP8 and FADD like apoptosis regulator. (489 aa)    
Predicted Functional Partners:
FADD
Fas associated via death domain.
    
 0.999
ITCH
Itchy E3 ubiquitin protein ligase.
    
 0.998
ENSANIP00000022474
annotation not available
   
 0.993
CASP10
Caspase 10.
   
 0.992
ENSANIP00000001376
annotation not available
   
 0.992
CASP8
Caspase 8.
   
 0.992
ENSANIP00000008300
annotation not available
    
 0.977
FASLG
Fas ligand.
    
 0.959
ATG3
Autophagy related 3.
    
 0.944
WWP2
WW domain containing E3 ubiquitin protein ligase 2.
    
 0.933
Your Current Organism:
Accipiter nisus
NCBI taxonomy Id: 211598
Other names: A. nisus, Eurasian sparrowhawk
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.