Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HGFHepatocyte growth factor. (726 aa)    
Predicted Functional Partners:
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.999
MST1R
Macrophage stimulating 1 receptor.
    
 0.985
EGF
Epidermal growth factor.
    
 0.970
IGF1
Insulin like growth factor 1.
   
 
 0.964
HGFAC
HGF activator.
   
 0.962
GAB1
GRB2 associated binding protein 1.
    
 0.953
NTRK3
Neurotrophic receptor tyrosine kinase 3.
    
 0.951
FLT4
Fms related tyrosine kinase 4.
     
 0.951
KDR
Kinase insert domain receptor.
     
 0.951
VEGFC
Vascular endothelial growth factor C.
     
 0.950
Your Current Organism:
Accipiter nisus
NCBI taxonomy Id: 211598
Other names: A. nisus, Eurasian sparrowhawk
Server load: low (20%) [HD]