STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRASKRAS proto-oncogene, GTPase. (188 aa)    
Predicted Functional Partners:
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.991
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.988
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 0.988
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.983
PIK3CD
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.
    
 0.973
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
    
 0.970
NF1
Neurofibromin 1.
    
 0.970
RASSF5
Ras association domain family member 5.
    
 0.968
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
    
 0.960
RALBP1
ralA binding protein 1.
    
 0.954
Your Current Organism:
Accipiter nisus
NCBI taxonomy Id: 211598
Other names: A. nisus, Eurasian sparrowhawk
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.