STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO11SPO11 initiator of meiotic double stranded breaks. (381 aa)    
Predicted Functional Partners:
WDR61
WD repeat domain 61.
    
 
 0.927
DMC1
DNA meiotic recombinase 1.
    
 0.891
TOP2B
DNA topoisomerase II beta.
    
 0.883
TOP2A
DNA topoisomerase II alpha.
    
 0.883
RAD51
RAD51 recombinase.
    
 0.858
XRCC3
X-ray repair cross complementing 3.
    
 0.838
MRE11
MRE11 homolog, double strand break repair nuclease.
   
 0.831
ENSANIP00000009418
annotation not available
    
 
 0.828
ENSANIP00000023621
annotation not available
    
 0.827
MYRF
Myelin regulatory factor.
    
 
 0.824
Your Current Organism:
Accipiter nisus
NCBI taxonomy Id: 211598
Other names: A. nisus, Eurasian sparrowhawk
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.