APH_0044 protein (Anaplasma phagocytophilum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

APH_0044

Identified by match to protein family HMM PF00361. (495 aa)

Predicted Functional Partners:

APH_0344

0.994

APH_0348

0.992

APH_1015

0.991

APH_0342

0.988

APH_0341

0.967

APH_0181

0.929

nuoL

0.924

nuoI

0.779

nuoB

0.596

nuoD

0.555

Your Current Organism:

Anaplasma phagocytophilum

NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APH_0044	APH_0181	APH_0044	APH_0181	Identified by match to protein family HMM PF00361.	Identified by match to protein family HMM PF00361.	0.929
APH_0044	APH_0341	APH_0044	APH_0341	Identified by match to protein family HMM PF00361.	Putative monovalent cation/proton antiporter, MrpF/PhaF subunit; Identified by match to protein family HMM PF04066.	0.967
APH_0044	APH_0342	APH_0044	APH_0342	Identified by match to protein family HMM PF00361.	Monovalent cation/proton antiporter, MnhG/PhaG subunit.	0.988
APH_0044	APH_0344	APH_0044	APH_0344	Identified by match to protein family HMM PF00361.	Putative monovalent cation/proton antiporter; Identified by similarity to GB:AAS14942.1; match to protein family HMM PF00420.	0.994
APH_0044	APH_0348	APH_0044	APH_0348	Identified by match to protein family HMM PF00361.	Identified by match to protein family HMM PF00361.	0.992
APH_0044	APH_1015	APH_0044	APH_1015	Identified by match to protein family HMM PF00361.	Na+/H+ ion antiporter family protein; Identified by match to protein family HMM PF01899.	0.991
APH_0044	nuoB	APH_0044	APH_0520	Identified by match to protein family HMM PF00361.	NADH dehydrogenase I, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.596
APH_0044	nuoD	APH_0044	APH_0732	Identified by match to protein family HMM PF00361.	NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.	0.555
APH_0044	nuoI	APH_0044	APH_0801	Identified by match to protein family HMM PF00361.	NADH dehydrogenase I, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.779
APH_0044	nuoL	APH_0044	APH_0437	Identified by match to protein family HMM PF00361.	NADH dehydrogenase I, L subunit; Identified by similarity to SP:P29924; match to protein family HMM PF00361; match to protein family HMM PF00662; match to protein family HMM TIGR01974.	0.924
APH_0181	APH_0044	APH_0181	APH_0044	Identified by match to protein family HMM PF00361.	Identified by match to protein family HMM PF00361.	0.929
APH_0181	APH_0341	APH_0181	APH_0341	Identified by match to protein family HMM PF00361.	Putative monovalent cation/proton antiporter, MrpF/PhaF subunit; Identified by match to protein family HMM PF04066.	0.894
APH_0181	APH_0342	APH_0181	APH_0342	Identified by match to protein family HMM PF00361.	Monovalent cation/proton antiporter, MnhG/PhaG subunit.	0.962
APH_0181	APH_0344	APH_0181	APH_0344	Identified by match to protein family HMM PF00361.	Putative monovalent cation/proton antiporter; Identified by similarity to GB:AAS14942.1; match to protein family HMM PF00420.	0.980
APH_0181	APH_0348	APH_0181	APH_0348	Identified by match to protein family HMM PF00361.	Identified by match to protein family HMM PF00361.	0.987
APH_0181	APH_1015	APH_0181	APH_1015	Identified by match to protein family HMM PF00361.	Na+/H+ ion antiporter family protein; Identified by match to protein family HMM PF01899.	0.962
APH_0181	nuoB	APH_0181	APH_0520	Identified by match to protein family HMM PF00361.	NADH dehydrogenase I, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.976
APH_0181	nuoD	APH_0181	APH_0732	Identified by match to protein family HMM PF00361.	NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.	0.976
APH_0181	nuoI	APH_0181	APH_0801	Identified by match to protein family HMM PF00361.	NADH dehydrogenase I, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.976
APH_0341	APH_0044	APH_0341	APH_0044	Putative monovalent cation/proton antiporter, MrpF/PhaF subunit; Identified by match to protein family HMM PF04066.	Identified by match to protein family HMM PF00361.	0.967