Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
APH_0044Identified by match to protein family HMM PF00361. (495 aa)    
Predicted Functional Partners:
APH_0344
Putative monovalent cation/proton antiporter; Identified by similarity to GB:AAS14942.1; match to protein family HMM PF00420.
 
 
 0.992
APH_1015
Na+/H+ ion antiporter family protein; Identified by match to protein family HMM PF01899.
 
 
 0.991
APH_0342
Monovalent cation/proton antiporter, MnhG/PhaG subunit.
 
 
 0.985
APH_0348
Identified by match to protein family HMM PF00361.
 
  
 0.981
APH_0181
Identified by match to protein family HMM PF00361.
 
 
0.941
nuoL
NADH dehydrogenase I, L subunit; Identified by similarity to SP:P29924; match to protein family HMM PF00361; match to protein family HMM PF00662; match to protein family HMM TIGR01974.
 
0.932
APH_0341
Putative monovalent cation/proton antiporter, MrpF/PhaF subunit; Identified by match to protein family HMM PF04066.
  
 
 0.923
nuoI
NADH dehydrogenase I, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.764
nuoB
NADH dehydrogenase I, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
   0.561
nuoD
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
   
   0.536
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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