STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APH_0051Iron-binding protein; Identified by similarity to GB:AAD03802.1; match to protein family HMM PF01547. (336 aa)    
Predicted Functional Partners:
APH_1045
ABC transporter, permease protein; Identified by match to protein family HMM PF00528.
 
 
 0.996
APH_0986
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; Belongs to the ABC transporter superfamily.
 
 
 0.964
APH_0052
Conserved hypothetical protein; Identified by similarity to GB:CAC47765.1; match to protein family HMM PF03966; Belongs to the UPF0434 family.
       0.773
APH_1159
Peptidase, M16 family; Identified by match to protein family HMM PF00675; match to protein family HMM PF05193.
      
 0.632
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.612
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
     
 0.595
xerD
Tyrosine recombinase XerD; Identified by similarity to SP:P21891; match to protein family HMM PF00589; match to protein family HMM PF02899; Belongs to the 'phage' integrase family.
     
 0.592
rnhA
Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
      
 0.549
dnaE
DNA polymerase III, alpha subunit; Identified by match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.
      
 0.549
trxB
Thioredoxin-disulfide reductase; Identified by similarity to SP:P09625; match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
   
    0.520
Your Current Organism:
Anaplasma phagocytophilum
NCBI taxonomy Id: 212042
Other names: A. phagocytophilum str. HZ, Anaplasma phagocytophilum HZ, Anaplasma phagocytophilum str. HZ
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.